THERAPY DOSSIER · th-eb98500b187f

Allogeneic particulate acellular dermal matrix prepared in defined gauges

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Wound
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 8

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT01561287 ↗PHASE4completed

A Comparison of Dermal Autograft to Commercially Available Dermal Allograft (AlloDerm) in Breast Reconstruction

Mastectomy Related Lymphedema · Breast Reconstruction · Breast Cancer

Enrolment: 48 · Results not recorded

NCT01987700 ↗PHASE4completed

Flex HD Human Acellular Dermal Matrix vs Strattice Porcine ADM in Repair of Large Abdominal Wall Hernias

Hernia of Abdominal Wall

Enrolment: 120 · Results not recorded

NCT06241196 ↗PHASE2unknown

Vestibular Socket Therapy Using Acellular Dermal Matrix (Alloderm) Versus Connective Tissue Graft

Immediate Implant

Enrolment: 10 · Results not recorded

NCT02360358 ↗PHASE1/PHASE2terminated

Cultured Autologous Skin (Tiscover) and Acellular Dermal Matrix (AS210) in Chronic (Arterio-)Venous Ulcers

Varicose Ulcer

Enrolment: 8 · Results not recorded

NCT01572298 ↗NAcompleted

Alveolar Ridge Augmentation Using Tenting Screws, Acellular Dermal Matrix and Combination Particulate Grafts

Dental Alveolus · Oral Surgical Procedures, Preprosthetic

Enrolment: 34 · Results not recorded

NCT01175720 ↗NAcompleted

Two Surgical Techniques With Acellular Dermal Matrix Graft in the Treatment of Gingival Recessions

Gingival Recession

Enrolment: 15 · Results not recorded

NCT02139748 ↗NAcompleted

Implant Placement and Simultaneous Grafting Using Acellular Dermal Matrix Allograft +/- Bovine Xenograft

Dental Implants

Enrolment: 28 · Results not recorded

NCT07345026 ↗NAnot yet recruiting

Clinical Efficacy of Acellular Dermal Matrix (SureDerm BCS) in Breast-Conserving Surgery

Breast Neoplasms · Mastectomy, Segmental

Enrolment: 116 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 22903602 ↗2012Reported benefit

Regeneration of mature dermis by transplanted particulate acellular dermal matrix in a rat model of skin defect wound.

RatWoundSprague-DawleyMalen = 12 male recipient rats, experimental group n = 6 and contro…Implantation into the full-thickness skin defect, covered with vaseline gauze and povidone-iodine gauzeAt the time of wounding

Model: Acute full-thickness dorsal skin defect of original area 4 x 6 cm

Allogeneic particulate acellular dermal matrix used as a dermal regeneration template facilitated maturation and improved collagen bundle structure of the regenerated dermis at 20 weeks after surgery. The preparation method produced particles with a narrower size distribution than previously report…

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.

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