Antioxidant carbon particles improve cerebrovascular dysfunction following traumatic brain injury.
RatTBIUnspecifiedIntravenous, 5 minute tail vein administration2 mg/kg, single doseAt the beginning of blood resuscitation, simulating hospital care after injury…
Model: Mild traumatic brain injury combined with haemorrhagic hypotension and staged resuscitation, including intravenous lactated Ringer's solution followed by oxygenation and blood reinfusion
A single 2 mg/kg intravenous dose of PEG-HCCs given at the start of resuscitation rapidly restored cerebral blood flow and normalised superoxide and nitric oxide levels compared with vehicle.
Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.