Neuroprotective effects of sulforaphane after contusive spinal cord injury.
RatSpinal cord injuryContusionSprague-DawleyFemaleSystemic administration10 or 50 mg/kg10 minutes and 72 hours after contusion
Model: Contusive spinal cord injury
Sulforaphane at 50 mg/kg produced acute and long-term benefit, upregulating the phase 2 antioxidant response at the injury site, decreasing inflammatory messenger RNA including MMP-9, inactivating urinary macrophage migration inhibitory factor tautomerase activity, enhancing hindlimb locomotor func…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.