Spinal duraplasty with two novel substitutes restored locomotor function after acute laceration spinal cord injury in rats.
RatSpinal cord injuryHemisection / partialSprague-DawleyFemaleSurgical implantation as dural patch at the lesion site
Model: Acute laceration spinal cord injury with dural tear, repaired by duraplasty
Both duraplasty substitutes restored locomotor function on the BBB scale and re-established neural conduction on motor-evoked potentials by 8 weeks; DHAM-BMSCs reduced total lesion and cystic volumes by nearly 10-fold versus control (p < 0.01), with increased neurotrophic factors and NF-200-positiv…
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.