Hepatoprotective effect of the ethanol extract of Vitis thunbergii on carbon tetrachloride-induced acute hepatotoxicity in rats through anti-oxidative activities.
RatChemical/toxinSprague-DawleyMaleOral administration
Model: Carbon tetrachloride (CCl4) induced acute hepatotoxicity
Oral EVT significantly decreased ALT and AST, reduced hepatic oxidative stress and increased catalase, superoxide dismutase, glutathione peroxidase and glutathione. Serum TNF-alpha, IL-1beta and nitric oxide fell, iNOS and COX-2 expression was blocked, and fatty degeneration, cytoplasmic vacuolisat…
Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.