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PRECLINICAL PUBLICATION · 2012

Hydrogen-rich saline reduces the oxidative stress and relieves the severity of trauma-induced acute pancreatitis in rats.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22695421 ↗2012Reported benefit

Hydrogen-rich saline reduces the oxidative stress and relieves the severity of trauma-induced acute pancreatitis in rats.

RatOtherWistarMaleIntraperitoneal

Model: Traumatic pancreatitis induced by controlled high pressure air impact

Intraperitoneal hydrogen-rich saline improved survival rate and histopathological findings and reduced plasma cytokine concentrations. Plasma amylase and lipase were not markedly inhibited, but pancreatic malondialdehyde fell and endogenous glutathione and superoxide dismutase were recruited.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.