Nanohybrids of silver particles immobilized on silicate platelet for infected wound healing.
MouseBurnUnspecifiedBALB/cMalen = Seven treatment groups; results expressed as mean and stand…Topical, applied to the wound bed as a dressing2 mg/ml silver preparation coated on the dressing, giving a…One day after wounding and bacterial dressing application
Model: Staphylococcus aureus infected deep partial-thickness burn (iron plate 1.5 x 1.5 cm at 180 degrees C for 20 s) and full-thickness 1.5 x 1.5 cm excision wound
AgNP/NSP was superior for wound appearance and gave the smallest excision wound area (5 plus or minus 3.5 mm) at days 5, 7 and 15, but wound healing rates, VEGF-A and TGF-beta1 levels were similar to Aquacel and silver sulfadiazine. The nanohybrid showed a trend to lower cytotoxicity at 8.75 ppm si…
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