Therapeutic potential of ginger against renal injury induced by carbon tetrachloride in rats.
RatChemical/toxinWistar albinoMalen = 60 male rats in 10 groups of 6Oral200 mg/kg bodyweight per extract; silymarin reference 100 m…Administered concurrently with CCl4 for the same six-week duration
Model: Carbon tetrachloride induced nephrotoxicity (500 microlitre CCl4 diluted 1:9 v/v in olive oil, intraperitoneal, twice weekly for six weeks)
CCl4 reduced glutathione by 57.53% and superoxide dismutase by 54.04% and raised lipid peroxides by 212.26%, with urea up 44.60%, creatinine up 43.70%, serum protein down 23.40%, PGE2 up 23.11% and collagen deposition 60.2%. Ethanol extract gave the greatest improvement (GSH 39.72%, LPO 184.01%, SO…
Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.