THERAPY DOSSIER · th-cf2f2cffb10d

Zingiber officinale (ginger) rhizome successive extracts: petroleum ether, chloroform and 95% ethanol

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Chemical/toxin
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 5

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT07190495 ↗PHASE4recruiting

Preoperative Ginger for Prevention of Postoperative Nausea and Vomiting in Laparoscopic Cholecystectomy

Postoperative Nausea and Vomiting

Enrolment: 102 · Results not recorded

NCT00958685 ↗PHASE2completed

Effect of Enteral Feeding With Ginger Extract in Acute Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome

Enrolment: 32 · Results not recorded

NCT03548363 ↗NAcompleted

Double-blind RCT of Gingest (ginger rhizome extract) on Symptoms of Dyspepsia

Dyspepsia · Epigastric Fullness · Bloating · Epigastric Pain

Enrolment: 150 · Results not recorded

NCT05880589 ↗NAunknown

Milk Secretory Supplement Containing Fenugreek, Banana Flower and Ginger Extract in Breast-feeding Volunteers

Lactation

Enrolment: 24 · Results not recorded

NCT05872464 ↗NAunknown

Artificial Saliva Containing Cumin and Ginger Extract in Head and Neck Cancer Patients With Xerostomia

Xerostomia

Enrolment: 52 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 22566780 ↗2012Reported benefit

Therapeutic potential of ginger against renal injury induced by carbon tetrachloride in rats.

RatChemical/toxinWistar albinoMalen = 60 male rats in 10 groups of 6Oral200 mg/kg bodyweight per extract; silymarin reference 100 m…Administered concurrently with CCl4 for the same six-week duration

Model: Carbon tetrachloride induced nephrotoxicity (500 microlitre CCl4 diluted 1:9 v/v in olive oil, intraperitoneal, twice weekly for six weeks)

CCl4 reduced glutathione by 57.53% and superoxide dismutase by 54.04% and raised lipid peroxides by 212.26%, with urea up 44.60%, creatinine up 43.70%, serum protein down 23.40%, PGE2 up 23.11% and collagen deposition 60.2%. Ethanol extract gave the greatest improvement (GSH 39.72%, LPO 184.01%, SO…

Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.

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