Plasminogen is a key proinflammatory regulator that accelerates the healing of acute and diabetic wounds.
MouseBurnUnspecifiedC57BL/6 wild-type and a mouse model of diabetesSystemic administration
Model: Acute burn wound in wild-type mice and chronic diabetic wound in a mouse model of diabetes
Systemic administration of additional plasminogen accelerated healing of acute burn wounds in wild-type mice and improved healing of chronic diabetic wounds in a mouse model of diabetes, acting through potentiation of the early inflammatory response.
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