Effect of curcumin on lipid peroxidation, early ultrastructural findings and neurological recovery after experimental spinal cord contusion injury in rats.
RatSpinal cord injuryContusionWistar albinoFemalen = 40 rats across 5 groupsCurcumin plus dimethyl sulfoxide 300 mg/kg; dimethyl sulfox…
Model: Spinal cord contusion by 50 g/cm weight drop
Curcumin significantly decreased lipid peroxidation in the first 24 h and was more effective than dimethyl sulfoxide or methylprednisolone for this endpoint. Neurological scores did not differ between treated and control groups and dimethyl sulfoxide was better at minimising ultrastructural change.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.