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PRECLINICAL PUBLICATION · 2012

Docosahexaenoic acid, but not eicosapentaenoic acid, reduces the early inflammatory response following compression spinal cord injury in the rat.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22404382 ↗2012Mixed findings

Docosahexaenoic acid, but not eicosapentaenoic acid, reduces the early inflammatory response following compression spinal cord injury in the rat.

RatSpinal cord injuryCompressionSprague-DawleyFemaleIntravenous250 nmol/kg for both DHA and EPA30 min after injury

Model: T12 compression spinal cord injury after laminectomy

DHA reduced epicentre neutrophils and plasma C-reactive protein, EPA did not, and neither fatty acid normalised the acute cytokine or hepatic inflammatory response.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.