PRECLINICAL PUBLICATION · 2012

An acute negative bystander effect of gamma-irradiated recipients on transplanted hematopoietic stem cells.

Mouse / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 22374698 ↗2012Reported benefit

MouseRadiationC57BL/6 and congenic strains

Model: Total body irradiation as host conditioning before haematopoietic stem cell transplantation

N-acetylcysteine, or ectopic catalase overexpression, improved the function of haematopoietic stem cells transplanted into irradiated hosts.

Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.