The effect of hyperbaric oxygen on neuroregeneration following acute thoracic spinal cord injury.
RatSpinal cord injuryCompressionSprague-Dawleymalehyperbaric chamberpreoperative treatment for 5 days before injury and postoperative treatment for…
Model: acute thoracic spinal cord injury induced by extradural aneurysm clip application at the T9-T11 level
Hyperbaric oxygen reduced nitric oxide synthase and nitric oxide activity in injured cord tissue, with reductions in superoxide dismutase and glutathione peroxidase in the treated groups, and improved BBB locomotor scores in the postoperative and combined treatment groups.
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