Alleviation of lung injury by glycyrrhizic acid in benzo(a)pyrene exposed rats: Probable role of soluble epoxide hydrolase and thioredoxin reductase.
RatChemical/toxinWistarMaleOral50 and 100 mg/kg body weight
Model: Intratracheal instillation of benzo(a)pyrene causing acute lung injury
Glycyrrhizic acid suppressed caspase activities in lung tissue, lowered lavage total protein, cell counts, elastase, lactate dehydrogenase and alkaline phosphatase, restored phospholipid content and improved histology after benzo(a)pyrene exposure.
Extraction: extract · Supplied extraction confidence: 0.78. Machine-extracted fields require source verification.