A fragment of secreted Hsp90alpha carries properties that enable it to accelerate effectively both acute and diabetic wound healing in mice.
MouseWoundHairless and nude miceTopical applicationAfter wounding
Model: Acute excisional skin wounds and diabetic wounds
Topical F-5 peptide accelerated closure of both acute and diabetic wounds in mice substantially more than PDGF-BB, attributed to recruitment of both epidermal and dermal cells and to migration that resisted TGF-beta and hyperglycaemic inhibition.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.