Cerebral metabolism after early decompression craniotomy following controlled cortical impact injury in rats.
RatTBIControlled cortical impactSprague-DawleyMaleSurgicalVery early after trauma
Model: Moderate controlled cortical impact injury
Controlled cortical impact caused an immediate sustained fall in glucose and rise in lactate/pyruvate ratio with delayed increases in lactate and glutamate that recovered by 60 min; decompression craniotomy significantly reduced the rise in intracranial pressure but no significant benefit on metabo…
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