Multi-centre prospective randomised trial of early decompressive craniectomy in patients with severe traumatic brain injury
Brain Injuries
Enrolment: 155 · Results not recorded
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Procedure
6 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Brain Injuries
Enrolment: 155 · Results not recorded
Head Injury Trauma
Enrolment: 20 · Results not recorded
Subarachnoid Hemorrhage, Aneurysmal
Enrolment: 60 · Results not recorded
Traumatic Brain Injury · Middle Cerebral Artery Stroke · Intracranial Hypertension
Enrolment: 17 · Results not recorded
Traumatic Brain Injury
Enrolment: 240 · Results not recorded
Brain Hemorrhage
Enrolment: 1000 · Results not recorded
Cerebellar Stroke
Enrolment: 72 · Results not recorded
Brain Edema
Enrolment: 88 · Results not recorded
Intracranial Pressure Increase
Enrolment: 48 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Moderate controlled cortical impact injury
Controlled cortical impact caused an immediate sustained fall in glucose and rise in lactate/pyruvate ratio with delayed increases in lactate and glutamate that recovered by 60 min; decompression craniotomy significantly reduced the rise in intracranial pressure but no significant benefit on metabo…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.