Docosahexaenoic acid pretreatment confers protection and functional improvements after acute spinal cord injury in adult rats.
RatSpinal cord injuryContusionSprague-DawleyFemaleIntravenousPretreatment, administered before injury
Model: Acute contusive spinal cord injury in adult rats, with outcomes targeted at cellular and molecular events during the first week after injury
Docosahexaenoic acid pretreatment reduced acute functional deficits, with significantly improved Basso-Beattie-Bresnahan scores and detection of transcranial magnetic motor evoked potentials, and at 7 days post-injury significantly increased white matter sparing, axonal preservation and survival of…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.