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PRECLINICAL PUBLICATION · 2011

Transplantation of undifferentiated and induced human exfoliated deciduous teeth-derived stem cells promote functional recovery of rat spinal cord contusion injury model.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21970342 ↗2011Reported benefit

Transplantation of undifferentiated and induced human exfoliated deciduous teeth-derived stem cells promote functional recovery of rat spinal cord contusion injury model.

RatSpinal cord injuryContusionWistarMaleTransplanted in the acute phase after contusion injury, with assessment up to 5…

Model: Acute contusive spinal cord injury in rats at the thoracic level

Both SHED and induced SHED groups showed significant locomotor functional recovery relative to vehicle and control groups, with the induced SHED group in a better state than the undifferentiated SHED group. Grafted cells showed neuronal and glial differentiation, and the induced SHED group had incr…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.