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PRECLINICAL PUBLICATION · 2011

Alleviation of cisplatin-induced acute kidney injury using phytochemical polyphenols is accompanied by reduced accumulation of indoxyl sulfate in rats.

Rat / Chemical/toxin

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21858734 ↗2011Reported benefit

Alleviation of cisplatin-induced acute kidney injury using phytochemical polyphenols is accompanied by reduced accumulation of indoxyl sulfate in rats.

RatChemical/toxinSprague-DawleyMaleOral-24, -1, 24 and 48 h around cisplatin injection

Model: Cisplatin (10 mg/kg i.p.)-induced acute kidney injury

Oral quercetin suppressed indoxyl sulfate accumulation and alleviated cisplatin-induced acute kidney injury.

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.