PRECLINICAL PUBLICATION · 2011

17beta-Estradiol administration attenuates seawater aspiration-induced acute lung injury in rats.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21820073 ↗2011Reported benefit

RatOtherSprague-DawleyMaleIntraperitoneal5 mg/kg20 min after seawater instillation

Model: Seawater aspiration-induced acute lung injury

17beta-estradiol downregulated aquaporins 1 and 5 and attenuated seawater aspiration-induced acute lung injury and oedema.

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.