PRECLINICAL PUBLICATION · 2011

Poloxamer 188 facilitates the repair of alveolus resident cells in ventilator-injured lungs.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21778295 ↗2011Mixed findings

RatOtherSprague-DawleyFemalen = 74 rats; 18 isolated lungsInfusionDuring ventilation

Model: Ventilator-induced lung injury

Poloxamer 188 promoted alveolar cell membrane repair but did not improve lung mechanics or vascular barrier in live animals.

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.