Trial title not recorded
Chronic Heart Failure
Enrolment: 10 · Results not recorded
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Drug · No ChEMBL mechanism_of_action record. Non-ionic triblock copolymer (polymer_flag=1, structure_type NONE, USAN stem '-mer') acting as a membrane-sealing and rheological agent rather than via a defined molecular target. The purified form vepoloxamer (MST-188) reached phase 3.
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Chronic Heart Failure
Enrolment: 10 · Results not recorded
Duchenne Muscular Dystrophy
Enrolment: 2 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Ventilator-induced lung injury
Poloxamer 188 promoted alveolar cell membrane repair but did not improve lung mechanics or vascular barrier in live animals.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.