PRECLINICAL PUBLICATION · 2011

The effect of a flavonoid fractions diosmin + hesperidin on radiation-induced acute proctitis in a rat model.

Rat / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21768702 ↗2011Reported benefit

RatRadiationSprague-DawleyFemalen = 34Oral (orogastric)100 mg/kg/dayFrom 1 day before irradiation until day 15

Model: Single 17.5 Gy pelvic irradiation-induced acute proctitis

Diosmin plus hesperidin reduced morphological inflammatory changes and may protect against radiation-induced acute proctitis.

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.