Tri Thien Duoc Capsules in Grade II Internal Haemorrhoids With Bleeding Compared to Diosmin
Grade II Internal Hemorrhoids With Bleeding
Enrolment: 172 · Results not recorded
Loading the evidence…
Nutraceutical · ChEMBL mechanism record: mechanism_of_action 'Unknown'. Curator comment: natural flavone glycoside indicated for haemorrhoids, lymphoedema and varicose veins; anti-inflammatory, antioxidant, antimutagenic and anti-hyperlipidaemic properties; inhibits P-gp-mediated efflux; protective in LPS-induced lung injury via inhibition of T cell receptors, pro-inflammatory cytokines and NF-kB activation
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Grade II Internal Hemorrhoids With Bleeding
Enrolment: 172 · Results not recorded
Deep Vein Thrombosis · Postthrombotic Syndrome
Enrolment: 90 · Results not recorded
Cancer Patients
Enrolment: 100 · Results not recorded
Infertility
Enrolment: 200 · Results not recorded
Rheumatoid Arthritis
Enrolment: 66 · Results not recorded
Helicobacter Pylori Infection
Enrolment: 46 · Results not recorded
Total Knee Arthroplasty · Venous Insufficiency of Leg
Enrolment: 190 · Results not recorded
Hemorrhoids, Internal
Enrolment: 69 · Results not recorded
Hematologic Malignancy · Bone Pain
Enrolment: 88 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Single 17.5 Gy pelvic irradiation-induced acute proctitis
Diosmin plus hesperidin reduced morphological inflammatory changes and may protect against radiation-induced acute proctitis.
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.
Model: Three models in one report: direct blunt trauma lung contusion; burn oedema of the rat foot; acute lymphoedema of the rat leg produced by lymphostasis
Diosmin considerably reduced interstitial oedema, tissue disorganisation and interstitial and air-space protein concentration in contused lung, with a greater effect at 200 than 50 mg/kg. In the oedema models the low dose (50 mg/kg) reduced burn oedema whereas the high dose (200 mg/kg) did not; bot…
Extraction: extract · Supplied extraction confidence: 0.82. Machine-extracted fields require source verification.