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← Studies/PMID 21725496
PRECLINICAL PUBLICATION · 2011

Contribution of nitric oxide synthase (NOS) activity in blood-brain barrier disruption and edema after acute ischemia/reperfusion in aortic coarctation-induced hypertensive rats.

Rat / Ischaemia-reperfusion

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Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21725496 ↗2011Reported benefit

Contribution of nitric oxide synthase (NOS) activity in blood-brain barrier disruption and edema after acute ischemia/reperfusion in aortic coarctation-induced hypertensive rats.

RatIschaemia-reperfusionCerebral (MCAO/stroke)Sprague-DawleyMaleIntraperitoneal1 mg/kgBefore MCAO

Model: Middle cerebral artery occlusion ischaemia/reperfusion in acute hypertensive (aortic coarctation) rats

L-NAME reduced cerebral infarction, oedema and blood-brain barrier disruption after ischaemia/reperfusion in acutely hypertensive rats.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.