PRECLINICAL PUBLICATION · 2011

Progesterone attenuates astro- and microgliosis and enhances oligodendrocyte differentiation following spinal cord injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Progesterone

PMID 21704617 ↗2011Reported benefit

Progesterone attenuates astro- and microgliosis and enhances oligodendrocyte differentiation following spinal cord injury.

RatSpinal cord injuryUnspecifiedSprague-DawleyMaleAcute (3 days) or chronic (21 days) administration

Progesterone inhibited astrocyte and microglial activation and promoted oligodendrocyte differentiation and remyelination after spinal cord injury in rats.

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.