PRECLINICAL PUBLICATION · 2011

IT delivery of ChABC modulates NG2 and promotes GAP-43 axonal regrowth after spinal cord injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Chondroitinase ABC (ChABC)

PMID 21630006 ↗2011Mixed findings

IT delivery of ChABC modulates NG2 and promotes GAP-43 axonal regrowth after spinal cord injury.

RatSpinal cord injuryCompressionWistarMaleIntrathecal (catheter)2, 3 and 4 days after injury

Model: Spinal cord compression injury

Intrathecal chondroitinase ABC decreased NG2 and enhanced GAP-43 axonal regrowth after spinal cord injury but did not significantly improve motor function.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.