Low dose estrogen prevents neuronal degeneration and microglial reactivity in an acute model of spinal cord injury: effect of dosing, route of administration, and therapy delay.

Low dose estrogen prevents neuronal degeneration and microglial reactivity in an acute model of spinal cord injury: effect of dosing, route of administration, and therapy delay.

Model: Acute spinal cord injury

Low-dose 17beta-estradiol reduced microglial activation and neuronal apoptosis after acute spinal cord injury in rats regardless of dose, route or timing.

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