Tissue plasminogen activator prevents white matter damage following stroke.
MouseIschaemia-reperfusionCerebral (MCAO/stroke)C57BL/6intravenous injection
Model: cerebral ischaemia (stroke)
tPA protected oligodendrocytes and rescued white matter from ischaemic lesions independently of its proteolytic activity.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.