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PRECLINICAL PUBLICATION · 2012

Dexamethasone pretreatment attenuates lung and kidney injury in cholestatic rats induced by hepatic ischemia/reperfusion.

Rat / Ischaemia-reperfusion

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21468628 ↗2012Reported benefit

Dexamethasone pretreatment attenuates lung and kidney injury in cholestatic rats induced by hepatic ischemia/reperfusion.

RatIschaemia-reperfusionHepaticSprague-DawleyMalen = 24 rats (3 groups)pretreatment before ischaemia-reperfusion

Model: hepatic ischaemia-reperfusion in cholestatic (bile duct ligation) rats

Dexamethasone pretreatment reduced hepatic ischaemia-reperfusion-induced lung and kidney injury and cytokine levels in cholestatic rats.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.