Intensive insulin treatment attenuates burn-initiated acute lung injury in rats: role of the protective endothelium.
RatBurnScaldSprague-DawleyMalesubcutaneoustitrated to blood glucose 5-7 mmol/Lafter injury
Model: scald burn (92 C water, 18 s) with acute lung injury
Intensive insulin treatment attenuated burn-induced lung injury by protecting microvascular endothelium and reducing apoptosis.
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