Erythropoietin administration modulates pulmonary Nrf2 signaling pathway after traumatic brain injury in mice.
MouseTBIWeight-drop / impact-accelerationMale5000 IU/kg30 min after TBI
Model: closed head weight-drop TBI with acute lung injury
rhEPO ameliorated TBI-induced acute lung injury and upregulated the pulmonary Nrf2 cytoprotective pathway.
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