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PRECLINICAL PUBLICATION · 2011

Erythropoietin administration modulates pulmonary Nrf2 signaling pathway after traumatic brain injury in mice.

Mouse / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21394044 ↗2011Reported benefit

Erythropoietin administration modulates pulmonary Nrf2 signaling pathway after traumatic brain injury in mice.

MouseTBIWeight-drop / impact-accelerationMale5000 IU/kg30 min after TBI

Model: closed head weight-drop TBI with acute lung injury

rhEPO ameliorated TBI-induced acute lung injury and upregulated the pulmonary Nrf2 cytoprotective pathway.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.