PRECLINICAL PUBLICATION · 2011

Acute skeletal injury is necessary for human adipose-derived stromal cell-mediated calvarial regeneration.

Mouse / Fracture

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21364415 ↗2011Mixed findings

MouseFractureCalvarial/defectnudeengraftment into defectimmediately (acute) or 8 weeks after defect creation (established)

Model: critical-size (4 mm) parietal calvarial defect (acute vs established)

Human ASCs healed acute calvarial defects but not established defects, linked to injury-induced BMP signalling.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.