THERAPY DOSSIER · th-73fdd83f253d

human adipose-derived stromal cells (ASCs), with platelet-rich plasma in vitro

Biologic

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Fracture
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 5

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT02865421 ↗PHASE2completed

Adipose tissue-derived stem cell (SVF) plus PRP hair restoration therapy for androgenetic alopecia

Androgenetic Alopecia

Enrolment: 22 · Results not recorded

NCT07544537 ↗PHASE2active not recruiting

Autologous bone marrow- and adipose tissue-derived MSCs versus PRP and standard therapy in organic erectile dysfunction

Erectile Dysfunction

Enrolment: 100 · Results not recorded

NCT03089762 ↗PHASE1completed

Intra-articular injection in the knee of adipose-derived stromal cells (SVF) plus platelet-rich plasma for osteoarthritis

Osteoarthritis

Enrolment: 10 · Results not recorded

NCT06524011 ↗NAunknown

Split-face comparative study of stromal vascular fraction-enriched PRP versus each alone in atrophic post-acne scars

Acne Scars - Atrophic

Enrolment: 30 · Results not recorded

NCT03078686 ↗NAunknown

Biocellular regenerative therapy using high-density PRP concentrates and cell-enriched emulsified adipose-derived tissue SVF in scarring alopecias and alopecia areata

Alopecia Areata · Scarring Alopecia

Enrolment: 60 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 21364415 ↗2011Mixed findings

Acute skeletal injury is necessary for human adipose-derived stromal cell-mediated calvarial regeneration.

MouseFractureCalvarial/defectnudeengraftment into defectimmediately (acute) or 8 weeks after defect creation (established)

Model: critical-size (4 mm) parietal calvarial defect (acute vs established)

Human ASCs healed acute calvarial defects but not established defects, linked to injury-induced BMP signalling.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.

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