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PRECLINICAL PUBLICATION · 2011

Hypoxic preconditioning with cobalt ameliorates hypobaric hypoxia induced pulmonary edema in rat.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21296072 ↗2011Reported benefit

Hypoxic preconditioning with cobalt ameliorates hypobaric hypoxia induced pulmonary edema in rat.

RatOtherSprague-DawleyMale12.5 mg/kg body weightPretreatment/preconditioning before hypoxia

Model: Hypobaric hypoxia (9142 m for 5 h at 24C) inducing high altitude pulmonary edema

Cobalt hypoxic preconditioning reduced vascular leakage, oedema and inflammation and increased protective HO-1 and metallothionein in hypobaric hypoxia.

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.