Evidence & regulatory context
- Mechanism
- Not recorded
- Target
- Not recorded
- Injury models
- Other
- Reported indication
- Not recorded
- First approval
- 1982
- Development stage
- Not recorded
- ChEMBL max phase
- 4 / 4 (development scale, not regulatory approval)
- Synonyms
- Cobalt chloride; Cobalt chloride (cocl2); Cobalt dichloride (cocl2); Cobaltous dichloride; Cobaltum muriaticum; NSC-51149
- Note
- Not recorded
Clinical trials 0
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
No linked human trial in this dataset.
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
RatOtherSprague-DawleyMale12.5 mg/kg body weightPretreatment/preconditioning before hypoxia
Model: Hypobaric hypoxia (9142 m for 5 h at 24C) inducing high altitude pulmonary edema
Cobalt hypoxic preconditioning reduced vascular leakage, oedema and inflammation and increased protective HO-1 and metallothionein in hypobaric hypoxia.
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.
