PRECLINICAL PUBLICATION · 2011

Role of amifostine on acute and late radiation nephrotoxicity: a histopathological study.

Rat / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21282738 ↗2011Reported benefit

RatRadiationWistarMalen = 30200 mg/kg30 min prior to irradiation

Model: Single dose 15 Gy unilateral kidney irradiation

Amifostine pretreatment markedly prevented radiation-induced acute and late glomerular, tubular and interstitial fibrotic damage in rat kidney.

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.