PRECLINICAL PUBLICATION · 2011

Induction of heat shock protein 70 inhibits ischemic renal injury.

Mouse / Ischaemia-reperfusion

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21270764 ↗2011Reported benefit

MouseIschaemia-reperfusionRenalC57BL/6 (including Hsp70 knockout)Before or after ischemic injury

Model: Transient renal ischemia (ischemia-reperfusion)

Inducing Hsp70 before or after ischaemic injury preserved renal function by attenuating tubular apoptosis, an effect absent in Hsp70 knockout mice.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.