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PRECLINICAL PUBLICATION · 2011

Delayed sodium pyruvate treatment improves working memory following experimental traumatic brain injury.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21241774 ↗2011Reported benefit

Delayed sodium pyruvate treatment improves working memory following experimental traumatic brain injury.

RatTBIControlled cortical impactSprague-DawleyMalen = 20Intraperitoneal1000 mg/kgOn days 4, 9 and 14 after injury, 1 hour before testing

Model: Unilateral cortical contusion injury

Delayed sodium pyruvate ameliorated TBI-induced working memory deficits in the spatial alternation task without changing contusion volume.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.