PRECLINICAL PUBLICATION · 2011

Delayed treatment with chondroitinase ABC reverses chronic atrophy of rubrospinal neurons following spinal cord injury.

Mouse / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21215745 ↗2011Reported benefit

MouseSpinal cord injuryComplete transectionYFP-H transgenicIntraspinal deliveryAcutely post-injury or after one month delay

Model: Unilateral rubrospinal tract transection

Both acute and delayed ChABC treatment rescued rubrospinal neurons from atrophy, reversing chronic cell-body atrophy after spinal cord injury.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.