Recombinant human erythropoietin prevents motor neuron apoptosis in a rat model of cervical sub-acute spinal cord compression.
RatSpinal cord injuryCompressionWistarFemalen = 80Intravenous500 units/kg (low) and 5000 units/kg (high)Day 7 post-surgery
Model: Cervical sub-acute spinal cord compression
rhEPO reduced motor neuron apoptosis and inflammatory cytokines and improved locomotor function after cervical spinal cord compression, with sustained low-dose benefit.
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