PRECLINICAL PUBLICATION · 2010

Systemic G-CSF treatment does not improve long-term outcomes after neonatal hypoxic-ischaemic brain injury.

Mouse / Ischaemia-reperfusion

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

Granulocyte colony-stimulating factor (G-CSF)

PMID 21145889 ↗2010No effect reported

Systemic G-CSF treatment does not improve long-term outcomes after neonatal hypoxic-ischaemic brain injury.

MouseIschaemia-reperfusionCerebral (MCAO/stroke)ICRSystemic200 micrograms/kg body weight1 h or 60 h after injury

Model: Neonatal hypoxic-ischaemic brain injury

G-CSF did not improve neurobehavioural outcomes or brain injury after neonatal hypoxia-ischaemia, and acute-phase injection increased hippocampal damage.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.