Antiepileptic and antiepileptogenic performance of carisbamate after head injury in the rat: blind and randomized studies.
RatTBIFluid percussionSprague-DawleyMaleProphylactic 2-week treatment from 15 min post-injury (antiepileptogenic); 1-we…
Model: Rostral parasagittal fluid percussion injury (contusive closed head injury) with post-traumatic epilepsy
Carisbamate showed no antiepileptogenic and only equivocal transient antiepileptic effects on post-traumatic epilepsy despite adequate plasma levels.
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