PebbleAtlas
PEBBLE / ATLAS
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PRECLINICAL PUBLICATION · 2010

Decorin, erythroblastic leukaemia viral oncogene homologue B4 and signal transducer and activator of transcription 3 regulation of semaphorin 3A in central nervous system scar tissue.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21115466 ↗2010Reported benefit

Decorin, erythroblastic leukaemia viral oncogene homologue B4 and signal transducer and activator of transcription 3 regulation of semaphorin 3A in central nervous system scar tissue.

RatTBIUnspecifiedSprague-DawleyFemaleIntracerebral infusionAfter injury

Model: Adult cerebral cortex traumatic scar tissue

Decorin infusion significantly reduced semaphorin 3A mRNA and protein expression in cortical scar tissue.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.