PRECLINICAL PUBLICATION · 2010

Tourniquet-induced acute ischemia-reperfusion injury in mouse skeletal muscles: Involvement of superoxide.

Mouse / Ischaemia-reperfusion

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 21036124 ↗2010Reported benefit

MouseIschaemia-reperfusionLimb / skeletal muscleC57BL/6MalePretreatment50 mg/kg eachBefore ischaemia-reperfusion

Model: Tourniquet-induced hind limb ischaemia-reperfusion (3 h ischaemia, 4 h reperfusion)

Tempol or coenzyme Q10 reduced superoxide, infarct size and mitochondrial dysfunction after tourniquet ischaemia-reperfusion.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.