PRECLINICAL PUBLICATION · 2010

Dilantin therapy in an experimental model of traumatic brain injury: effects of limited versus daily treatment on neurological and behavioral recovery.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 20964534 ↗2010Mixed findings

RatTBIControlled cortical impactSprague-DawleyMaleIntraperitoneal75 mg/kg day 0 then 50 mg/kgAcute (limited) versus daily chronic

Model: Controlled cortical impact traumatic brain injury

Limited acute phenytoin was beneficial while daily chronic phenytoin worsened recovery after TBI.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.