Comparative Trial of IV Lacosamide Versus Phenytoin for Seizure Management
Seizures
Enrolment: 3 · Results not recorded
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Drug · Sodium channel alpha subunit blocker (BLOCKER); direct interaction, disease efficacy true
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Seizures
Enrolment: 3 · Results not recorded
Chronic Idiopathic Axonal Polyneuropathy
Enrolment: 81 · Results not recorded
Healthy
Enrolment: 14 · Results not recorded
Healthy
Enrolment: 26 · Results not recorded
Primary Open Angle Glaucoma · Normal Tension Glaucoma
Enrolment: 200 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Controlled cortical impact traumatic brain injury
Limited acute phenytoin was beneficial while daily chronic phenytoin worsened recovery after TBI.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
Model: Surgical Achilles tendon rupture
Tendon healing was significantly better in the phenytoin group than in the injured control group on day 21 (p<0.05), with increased fibroblast numbers, fibrillar collagen synthesis and vascularity and suppressed inflammation.
Extraction: extract · Supplied extraction confidence: 0.78. Machine-extracted fields require source verification.