PRECLINICAL PUBLICATION · 2011

Early administration of L-arginine in experimental acute spinal cord injury impairs long-term motor function recovery.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

RatSpinal cord injuryUnspecifiedLong-EvansFemalen = 6 per groupIntravenous300 mg/kg per dose1 h, 24 h, or daily for 7 days after injury

Model: Moderate spinal cord injury

Early L-arginine worsened long-term locomotor recovery after spinal cord injury, suggesting neurotoxicity.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.